Memory Research Unit, Assistant Professor Kazumasa Z. Tanaka
Abstract
The Memory Research Unit aims to understand how memories are stored and used in the brain. The hippocampus, together with its related structures, plays a unique role in memories of past events. Nevertheless, its specific contribution remains unclear. Our unit aims to reveal the mechanism of memory by using multidisciplinary approaches in rodents.
During FY2019, we initiated setting up the laboratory. Outstanding scientists joined the unit and we keep recruiting more talents to build a diverse team in terms of both academic and cultural backgrounds. We are shifting to a phase for building up equipment and expect to complete by the end of FY2020.
記憶研究ユニットは、脳がどのように記憶を保存し、そして使うのかを理解しようとしています。中でも海馬は、その周辺領域とともに、過去の体験についての記憶に特別な役割を持っています。しかし、具体的にその役割が何なのかは未だ確かには分かっていません。私達の目標は、げっ歯類を使った分野横断的な研究アプローチを通して、記憶のメカニズムを明らかにすることです。
2019年度は研究室のセットアップに取り掛かりました。優れた科学者が研究室に加わり、今後も優秀な人材を集めることで学術的にも文化的にも多様な研究チームを作り上げていきます。現在は研究機材の設置に取り組んでおり、2020年度末までの完了を目指しています。
1. Staff
- Damien Mercier, Staff Scientist (Feb. 2020-)
- Hiroto Ashitomi, Technician (Mar. 2020-)
- Chie Narai, Research Unit Administrator
2. Collaborations
2.1 Characterization of the dendritic microstructure in the hippocampus
- Type of collaboration: Joint research
- Researchers:
- Professor, Masato Koike, Juntendo University
- Assistant Professor, Laxmi Kumar Parajuli, Juntendo University
- Team Leader, Thomas J. McHugh, RIKEN
- Team Leader, Akiko Hayashi-Takagi, RIKEN
2.2 Characterization of local connectivity of the hippocampal neurons
- Type of collaboration: Joint research
- Researchers:
- Team Leader, Thomas J. McHugh, RIKEN
- Team Leader, Andrea Benucci, RIKEN
- Research Scientist, Ryo Aoki, RIKEN
- Research Scientist, Vladislav Sekulic, RIKEN
3. Activities and Findings
3.1 Lab set-ups
In March 2020, lab space in the new Lab4 building became available for the Memory Research Unit. We are currently setting up lab equipment including high-density recording rigs & miniature microscopes, behavioral apparatus for mice, optogenetics, etc.
2020年3月、新しく完成したLab4研究棟内に記憶研究ユニットの研究スペースができました。現在、高密度電気生理記録設備や小型顕微鏡、マウス用行動実験設備、光遺伝学装置などの研究機器の設置に取り組んでいます。
4. Publications
4.1 Journals
- Tanaka, KZ. A father's odyssey. Science, Vol. 365, Issue 6449, pp. 194 doi:10.1177/1059712310397633 DOI: 10.1126/science.365.6449.194 (2019). [career essay]
- Tanaka, KZ. The heterogeneous representations in the hippocampus. Neuroscience Research (accepted) [invited review paper]
- Tanaka, KZ.*, Goode, TD.*, Sahay, A., McHugh, TJ. Hippocampal Memory: Indexing, Space and Engrams. Neuron (under review) [invited review paper, *equally contributed]
4.2 Books and other one-time publications
Nothing to report
4.3 Oral and Poster Presentations
- Kazumasa Z. Tanaka. Heterogeneous memory traces in the hippocampus, NEURO2019 (The 42nd Annual Meeting of the Japan Neuroscience Society & The 62nd Annual Meeting of the Japanese Society for Neurochemistry), Niigata, Japan, July 25-28 (2019).
Oral presentation.
Symposium "Neuronal Substrates for Episodic Memory", co-organized with Dr. Takashi Kitamura (University of Texas, Southwestern) - Kazumasa Z. Tanaka. The hippocampus and memory / Juggling research and parenting, Symposium organized by Society for Young researchers on Neuroscience, Tokyo, Japan, December 11 (2019).
Invited lecture.
5. Intellectual Property Rights and Other Specific Achievements
Nothing to report.
6. Meetings and Events
Nothing to report.
7. Other
Guest editor in Neuroscience Research, Vol 152, March 2020
"Technologies advancing neuroscience"
Thomas J. McHugh and Kazumasa Z. Tanaka