Unit News

Genomic analysis of a widespread species of zooplankton questions our assumptions about speciation and gene regulation.

Scientists at OIST and the Janelia Research Campus have shown that gene expression in a fruit fly embryo can be accurately and predictably tuned.

High-res genome catalogue captures long-distance calls between DNA segments that may influence diseases

As we grow, an intricate choreography of genetic controls begins to differentiate our cells, turning some genes off and others up to full-blast, eventually yielding fully-formed animals. Researchers at OIST are working to learn more about this choreography.

In a paper published yesterday in Science, a team of researchers that includes OIST's Nick Luscombe shows that the long-accepted view of how male fruit flies manipulate their genes’ activity should be revised. Their finding shows how cells use a single, crucial regulator to change the activity of large numbers of genes at the same time.

A team led by Nicholas Luscombe has answered a key question about the mechanism of genetic mutation and evolution. His new study shows that living things are able to tightly guard their most valuable genes, while leaving others more vulnerable to chance mutations.