Patent
1. Oegema, K., Shiau, A.K., Desai, A., Meitinger, F., and Davis, R.L., Methods of treating cancer with PLK4 inhibitors, PCT/US2018/064243
Publications
*equal contribution; #corresponding autors
1. Meitinger, F. #, Belal, H., Davis, R.L., Martinez, M.B., Shiau, A.K., Oegema, K. #, Desai, A#. (2024). Control of cell proliferation by memories of mitosis. Science 383 (6690):1441-1448.
2. Meitinger, F. *, Kong, D. *, Ohta, M. *, Desai, A., Oegema K., Loncarek, J. (2021) TRIM37 prevents formation of condensate-organized ectopic spindle poles to ensure mitotic fidelity. Journal of Cell Biology. 220(7):e202010180.
3. Kubo, N., Ishii, H., Xiong, X., Bianco, S., Meitinger, F., Hu, R., Hocker, J.D., Conte, M., Gorkin, D., Yu M., Li, B., Dixon, J.R., Hu, M., Nicodemi, M., Zhao, H., Ren, B. (2021). Promoter-proximal CTCF-binding Promotes Long-range-enhancer Dependent Gene Activation". Nat Struct Mol Biol, doi:10.1038/s41594-020-00539-5.
4. Watanabe, S. *, Meitinger, F. *, Shiau, A.K., Oegema, K.#, Desai, A.#. (2020). Centriole-independent mitotic spindle assembly relies on the PCNT-CDK5RAP2 pericentriolar matrix. Journal of Cell Biology. 219(12):e202006010.
5. Meitinger, F. #, Ohta, M., Lee, K.Y., Watanabe, S., Davis, R.L., Anzola, J.V., Kabeche, R., Jenkins, J., Shiau, A.K., Desai, A. #, Oegema, K. #. (2020). The ubiquitin ligase TRIM37 controls cancer-specific vulnerability to PLK4 inhibition. Nature 585:440-446.
Highlighted in Nature Reviews Drug Discovery and Cancer Discovery.
6. Gemble, S., Simon, A., Pennetier, C., Dumont, M., Hervé, S., Meitinger, F., Oegema, K., Rodriguez, R., Almouzni, G., Fachinetti, D., Basto, R. (2019). Centromere Dysfunction Compromises Mitotic Spindle Pole Integrity. Current Biology 29, 3072-3080 e3075
7. Fei, J., Ishii, H., Hoeksema, M.A., Meitinger, F., Kassavetis, G.A., Glass, C.K., Ren, B., and Kadonaga, J.T. (2018). NDF, a nucleosome-destabilizing factor that facilitates transcription through nucleosomes. Genes & Development 32, 682–694.
8. Kim, T., Lara-Gonzalez, P., Prevo, B., Meitinger, F., Cheerambathur, D.K., Oegema, K., and Desai, A. (2017). Kinetochores accelerate or delay APC/C activation by directing Cdc20 to opposing fates. Genes & Development 31, 1089-1094.
9. Meitinger, F., and Pereira, G. (2017). The septin-associated kinase Gin4 recruits Gps1 to the site of cell division. Molecular Biology of the Cell 28 (7), 883-889.
10. Meitinger, F., Anzola, J.V., Kaulich, M., Richardson, A., Stender, J.D., Benner, C., Glass, C.K., Dowdy, S.F., Desai, A., Shiau, A.K., Oegema, K. (2016). 53BP1 and USP28 mediate p53 activation and G1 arrest after centrosome loss or extended mitotic duration. Journal of Cell Biology 214, 155-166.
Highlighted and summarized in:
Soussi, T. and Kroemer, G. (2016) TP53 and 53BP1 Reunited. Trends in Cell Biology.
Strzyz, P. (2016) Cell Signalling to cell cycle arrest. Nature Reviews Molecular Cell Biology
Durocher, D. and Pelletier, L. (2016) 53BP1 Goes Back to its p53 Roots. Molecular Cell
Lambrus and B.G., Holland, A.J. (2017) A new mode of of mitotic Surveillance. Trends in Cell Biology
11. Meitinger, F., Khmelinskii, A., Morlot, S., Kurtulmus, B., Palani, S., Andres-Pons, A., Hub, B., Knop, M., Charvin, G., and Pereira, G. (2014). A memory system of negative polarity cues prevents replicative aging. Cell 159, 1056-1069.
Commented in:
Wedlich-Söldner, R. (2014). A longer life for yeast with good memory. Dev. Cell, 31:391-392.
12. Meitinger, F., Palani, S., Hub, B., and Pereira, G. (2013a). Dual function of the NDR-kinase Dbf2 in the regulation of the F-BAR protein Hof1 during cytokinesis. Molecular Biology of the Cell 24, 1290-1304.
13. Meitinger, F., Richter, H., Heisel, S., Hub, B., Seufert, W., and Pereira, G. (2013b). A safeguard mechanism regulates Rho GTPases to coordinate cytokinesis with the establishment of cell polarity. PLoS Biology 11, e1001495.
14. Mancini Lombardi, I., Palani, S., Meitinger, F., Darieva, Z., Hofmann, A., Sharrocks, A.D., and Pereira, G. (2013). Lre1 directly inhibits the NDR/Lats kinase Cbk1 at the cell division site in a phosphorylation-dependent manner. Current Biology, CB 23, 1736-1745.
15. Palani, S., Meitinger, F., Boehm, M.E., Lehmann, W.D., and Pereira, G. (2012). Cdc14-dependent dephosphorylation of Inn1 contributes to Inn1-Cyk3 complex formation. Journal of Cell Science 125, 3091-3096.
16. Meitinger, F., Boehm, M.E., Hofmann, A., Hub, B., Zentgraf, H., Lehmann, W.D., and Pereira, G. (2011). Phosphorylation-dependent regulation of the F-BAR protein Hof1 during cytokinesis. Genes & Development 25, 875-888.
17. Meitinger, F., Petrova, B., Lombardi, I.M., Bertazzi, D.T., Hub, B., Zentgraf, H., and Pereira, G. (2010). Targeted localization of Inn1, Cyk3 and Chs2 by the mitotic-exit network regulates cytokinesis in budding yeast. Journal of Cell Science 123, 1851-1861.
Commented in:
Bradbury, J. (2010). Mitotic-exit networks with cytokinesis. J. Cell Sci. 123, 1103e.
Review Articles
1. Belal, H., Ng, E.F.Y, Meitinger, F. (2024). 53BP1-mediated activation of the tumor suppressor p53. Curr Opin Cell Biol 2024, 91:102424.
2. Meitinger, F.#, and Palani, S. # (2016). Actomyosin ring driven cytokinesis in budding yeast. Seminars in Cell & Developmental Biology 53, 19-27. # corresponding authors
3. Meitinger, F., Palani, S., and Pereira, G. (2012). The power of MEN in cytokinesis. Cell Cycle 11, 219-228.
Book Chapters
1. Ng, E.F.Y, Meitinger, F. (2024). Genetic engineering and screening using base editing and inducible gene knockout. Methods Mol. Biol. In press
2. Meitinger, F., Palani, S., and Pereira, G. (2016). Detection of Phosphorylation Status of Cytokinetic Components. Methods Mol. Biol. 1369, 219-237.
3. Meitinger, F., and Pereira, G. (2016). Visualization of Cytokinesis Events in Budding Yeast by Transmission Electron Microscopy. Methods Mol. Biol. 1369, 87-95.