Publications
Selected publications
Full publication list (here):
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2025 |
AO Demkiv, S Toledo-Patino, E Medina-Carmona, A Berg, GP Pinto, Antonietta Parracino, Jose M Sanchez-Ruiz, Alvan C Hengge, Paola Laurino, Liam M Longo, Shina Caroline Lynn Kamerlin. " Redefining the Limits of Functional Continuity in the Early Evolution of P-Loop NTPases", Molecular Biology and Evolution. Just accepted!
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2024 |
M M Matthews, T G Kim, K Y Kim, V Meshcheryakov, H Alves Iha, M Tamai, D Sasaki, P Laurino, S Toledo-Patiño, M Collins, TY Hsieh, S Shibata, N Shibata, F Obata, J Fujii, T Ito, H Ito, H Ishikawa, M Wolf. "Engineered protein subunit COVID19 vaccine is as immunogenic as nanoparticles in mouse and hamster models", Scientific Reports. 14, 25528 (2024). https://doi.org/10.1038/s41598-024-76377-y
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2024 |
Toledo-Patiño S, Goetz SK, Shanmugaratnam S, Höcker B, Farías-Rico JA. "Molecular handcraft of a well-folded protein chimera". FEBS Letters. 2024 Mar 20. https://doi.org/10.1002/1873-3468.14856. E-publication ahead of print. PMID: 38508768. |
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2022 |
Toledo-Patino S, Pascarelli S, Uechi G-I, Laurino P. "Insertions and deletions mediated functional divergence of Rossmann fold enzymes". Proc Natl Acad Sci USA. 2022;119(48). https://doi.org/10.1073/pnas.2207965119 |
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2022
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Jayaraman V*, Toledo-Patino S*, Noda L, Laurino P. "Mechanism of protein evolution". Protein Science. https://doi.org/10.1002/pro.4362 |
| 2021 |
Chouhan PSB, Gade M, Martinez D, Toledo-Patino S, Laurino P. "Implications of divergence of methionine adenosyltransferase in archaea". FEBS Open Bio. https://doi.org/10.1002/2211-5463.13312 |
| 2020 |
Ferruz N, Lobos F, Lemm D, Toledo-Patino S, Farias-Rico J, Schmidt S, Höcker B. "Identification and analysis of natural building blocks for evolution-guided fragment-based protein design". JMB. https://doi.org/10.1016/j.jmb.2020.04.013 |
| 2019 |
Toledo-Patino S, Chaubey M, Coles M, Höcker B. "Reconstructing the remote origins of a fold singleton from a flavodoxin-like ancestor". Biochemistry. https://doi.org/10.1021/acs.biochem.9b00900 |
| 2017 |
Toledo-Patino S, Lobos F, Höcker B. "Building blocks of Nature: New proteins from conserved fragments". BioSpektrum. 2017;23(6). https://doi.org/10.1007/s12268-017-0847-8 |