Microglial precursors progressively colonize into the retina from 30 to 48 hours after fertilization.
Images of a zebrafish retina from 30 hours after fertilization (hpf) to 48 hpf. In the left column, the microglial precursors are tagged with purple fluorescence, whilst the developing zebrafish retina is green. The right upper image shows, at around 30 hpf, the first microglial precursors entering the eye via the blood vessels. The right lower image shows, at between 42 and 48 hpf, the microglial precursors colonizing the rest of the retina through areas undergoing neurogenesis.
Images of a zebrafish retina from 30 hours after fertilization (hpf) to 48 hpf. The microglial precursors are tagged with purple fluorescence, whilst the developing zebrafish retina is green. The right upper image shows, at around 30 hpf, the first microglial precursors entering the eye via the blood vessels. The right lower image shows, at between 42 and 48 hpf, the microglial precursors colonizing the rest of the retina through areas undergoing neurogenesis. This image appeared in the press release “From blood vessels as pathways to neurons as gatekeepers: Journey of immune cells in developing zebrafish revealed”.
Copyright OIST (Okinawa Institute of Science and Technology Graduate University, 沖縄科学技術大学院大学). Creative Commons Attribution 4.0 International License (CC BY 4.0).
