POC Projects | Okinawa Institute of Science and Technology OIST

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Round 13 (Starting in FY2025)

#	Project	Research Unit	Project Leader	Phase	Status
86	Fibroblast-to-Cardiomyocyte Reprogramming with Novel Gene Regulators	Synapse Biology Unit	Zacharie Taoufiq	Phase I	Ongoing
85	A novel synthesized peptide, PHDP5, as a potential treatment for Alzheimer’s Disease [EN/JP]	Neural Computation Unit	Chia Jung Chang	Phase II	Ongoing
84	Development of an Edge AI system for real-time detection of alien invasive anuran species	Biological Physics Theory Unit	Kosmas Deligkaris	Seed Phase	Awarded
83	Metal oxides as catalysts in mechanochemistry: developing cost-efficient and green techniques for smallmolecule drug synthesis	Coordination Chemistry and Catalysis Unit	Julia Khusnutdinova	Seed Phase	Awarded
82	Application of T-cell adaptation mechanisms to tumor microenvironment for cancer immunotherapy	Integrated Open Systems Unit	Naoyuki Taira	Phase I	Ongoing
81	Rydberg Atom – Optical Nanofiber based Single Photon Emitter	Light-Matter Interactions for Quantum Technologies Unit	Alexey Vylegzhanin	TPF	Awarded

Round 12 (Started in FY2024)

#	Project	Research Unit	Project Leader	Phase	Status
80	A novel algorithm to estimate wind speed	Fluid Mechanics Unit	Vishnu Ravindran	Seed Phase	Ongoing
79	Optimization of AAV Vector Production Using Riboswitch [EN/JP]	Nucleic Acid Chemistry and Engineering Unit	Yohei Yokobayashi	Seed Phase	Ongoing
78	Unlocking microbial PFAS-degradation with evolutionary approaches [EN/JP]	Protein Engineering and Evolution Unit	Paola Laurino and Paul Matthay	Seed Phase	Ongoing
77	Plastitective: Fast and efficient microplastic detection [EN/JP]	pi-Conjugated Polymers Unit	Samantha Phan	TPF	Ongoing
76	Development of peptide inhibitors to target neuroblastoma [EN/JP]	Cell Proliferation and Gene Editing Unit	Franz Meitinger	Seed Phase	Ongoing
75	Cyclic-1,3-dione derivatives conjugates with resins [EN/JP]	Chemistry and Chemical Bioengineering Unit	Fujie Tanaka	Seed Phase	Ongoing
74	Reducing Quadcopter Performance Degradation via Statistical Physics [EN/JP]	Nonlinear and Non-equilibrium Physics Unit	Mahesh Bandi	Seed Phase	Ongoing
73	iH2O2: Iron-catalyzed H2O2 production [EN/JP]	Organometallic Chemistry Group	Satoshi Takebayashi	Seed Phase	Ongoing
72	EbiSeq: Innovative Environmental Nucleic Acid Tools Improve Shrimp Farming [EN/JP]	Marine Climate Change Unit	Roger Huerlimann	Seed Phase	Ongoing
71	Accelerating Human Cardiac Regeneration with UD Proteomics-guided Stem Cell Programming [EN/JP]	Synapse Biology Unit	Zacharie Taoufiq	Seed Phase	Finished
70	A new small peptide, PHDP5, as a potential treatment of Alzheimer’s Disease [EN/JP]	Neural Computation Unit	Chia Jung Chang	Phase I	Finished
69	Ion trap and optics developments for quantum networking [EN/JP]	Experimental Quantum Information Physics Unit	Ezra Kassa	Seed Phase	Finished
68	Spin-based ultra-low noise amplifier for microwave quantum technologies [EN/JP]	Science and Technology Group	Yuimaru Kubo	Phase II	Ongoing

Round 11 (Started in FY2023)

#	Project	Research Unit	Project Leader	Phase	Status
67	Microwave masers and frequency combs for communications and sensing [EN/JP]	Quantum Machines Unit	Jason Twamley	Seed Phase	Finished
66	A hybrid 3D-nanofabrication technology for the development of 3D-scaffolds, hydrogels, and implants for research and medical applications [EN/JP]	Neural Circuit Unit	Lokesh Agrawal	Phase II	Ongoing
65	Search [EN/JP]	OIST Innovation	Sergey Zobnin	TPF	Ongoing
64	Microalgae as a functional ingredient to enhance nutritional and sensory properties of meat analogues [EN/JP]	Micro/Bio/Nanofluidics Unit	Davide Califano	Seed Phase	Finished
63	Development of effective therapeutic methodology using a series of siRNAs conjugated with nanoparticles [EN/JP]	Cell Signal Unit	Tadashi Yamamoto	Seed Phase	Finished
62	Design of E.coli strains able to efficiently degrade polyfluorinated compounds [EN/JP]	Protein Engineering and Evolution	Paola Laurino	Seed Phase	Finished
61	Opioid potentiators for enhancing analgesia and suppressing tolerance development of morphine and other opioids [EN/JP]	Membrane Cooperativity Unit	Peng Zhou	TPF	Ongoing
60	Okinawa Yarn Project [EN/JP]	Mechanics and Materials Unit	Hitomi Shinzato	TPF	Ongoing
59	Ion Trap and Optics Developments for Quantum Networking [EN/JP]	Experimental Quantum Information Physics	Ezra Kassa	Seed Phase	Finished
58	Spin-based millikelvin microwave quantum devices [EN/JP]	Science and Technology Group	Yuimaru Kubo	Phase I	Finished
57	Dissemination and implementation of Well Parent Japan (WPJ) [EN/JP]	Human Developmental Neurobiology Unit	Gail Tripp	Phase II	Finished

Round 10 (Started in FY2022)

#	Project	Research Unit	Project Leader	Phase	Status
56	Applied research on aging and age-related disease markers [EN/JP]	OIST Innovation	Takayuki Teruya	TPF	Finished
55	A novel viral vector for gene delivery specifically to neurons in the Central Nervous System [EN/JP]	Membrane Cooperativity Unit	Saahil Acharya	TPF	Finished
54	Personalized Synapse Proteomics of living psychiatric patients [EN/JP]	Cellular & Molecular Synaptic Function Unit	Zacharie Taoufiq	Phase II	Finished
53	Cost-effective and low maintenance scale-up advanced wastewater treatment and nutrient recovery for swine farms [EN /JP]	Biological Systems Unit	Mami Kainuma	Phase II	Finished
52	Development of a hybrid, grid-based, multi-nozzle, 3D nanofabrication system for 3D-scaffolds, hydrogels, and implants for tissue engineering	Molecular Neuroscience Unit	Lokesh Agrawal	Phase I	Finished
51	Tunable optical elements for imaging [EN/JP]	Quantum Machines Unit	Jason Twamley	Phase I	Finished

Round 9 (Started in FY2021)

#	Project	Research Unit	Project Leader	Phase	Status
50	Fiber endcap device for enabling atherectomy with a femtosecond laser [EN/JP]	Femtosecond Spectroscopy Unit	Viktoras Lisicovas	TPF	Finished
49	Development of protein micro/nanoarrays for high-throughput proteomics	Micro/Bio/Nanofluidics Unit	Shivani Sathish	TPF	Finished
48	An advanced wastewater treatment technology to help swine farmers meet impending discharge regulations [EN/JP]	Biological Systems Unit	Mami Kainuma	Phase I	Finished
47	Enhanced production of astaxanthin specialized entrapped yeast	Science and Technology Group	Eugene Kroll	Phase I	Finished
46	Verification of therapeutic approach for frailty based on metabolomic findings	G0 Cell Unit	Mitsuhiro Yanagida	Phase I	Finished
45	Development of a drug test platform by unraveling the molecular mechanisms of alpha-synuclein aggregation using an in vitro human brain organoid model	Optical Neuroimaging Unit	Jo Junghyun	Phase I	Finished
44	Mechanoresponsive materials to detect mechanical stress and damage in polymers	Coordination Chemistry and Catalysis Unit	Julia Khusnutdinova	Phase I	Finished

Round 8 (Started in FY2020)

#	Project	Research Unit	Project Leader	Phase	Status
43	A compact AI cytoscope for label-free prediction and tracking of cell phenotype and behavior	Micro/Bio/Nanofluidics Unit	Hsieh-Fu Tsai	TPF	Finished
42	Bio-Practical AppliCation Treatment Systems	Biological Systems Unit	David Simpson	TPF	Finished
41	Development of Methods for determining the structures of small compounds using mass and ion-mobility of fragment ions.	Evolutionary Neurobiology Unit	Eisuke Hayakawa	Phase II	Finished
40	Feasibility study for commercialization of OIST Rice	Plant Epigenetics Unit	Hidetoshi Saze	Phase II	Finished
39	Proteomics analyses of synapses purified from human iPSC-derived neurons.	Cellular & Molecular Synaptic Function Unit	Zacharie Taoufiq	Phase I	Finished
38	Development of air-stable organic glow-in-the-dark materials [EN/JP]	Organic Optoelectronics Unit	Ryota Kabe	ITR	Finished
37	Early detection of risk for mental disorders by computer mediated real-time social interaction [EN/JP]	Embodied Cognitive Science Unit	Tom Froese	ITR	Finished

Round 7 (Started in FY2019)

#	Project	Research Unit	Project Leader	Phase	Status
36	Application of atom economical Ru catalysis to economical synthesis of novel chemical matter	Science and Technology Group	Eugene Khaskin	Phase I	Finished
35	Development of Ducted Wave Energy Converter	Quantum Wave Microscopy Unit	Tsumoru Shintake	Phase II	Finished

Round 6 (Started in FY2019)

#	Project	Research Unit	Project Leader	Phase	Status
34	Spin-based cryogenic microwave amplifier for quantum technologies	Quantum Dynamics Unit	Yuimaru Kubo	ITR	Finished
33	The neuromuscular junction as a new target for treatment of Hereditary Motor and Sensory Neuropathy	Cell Signal Unit	Tadashi Yamamoto	ITR	Finished
32	Cost-effective production of anion exchange membranes for industrial applications	Biological Systems Unit	Peter Babiak	Phase II	Finished
31	Open source total gradient computation framework	Neural Computation Unit	Paavo Parmas	Phase I	Finished

Round 5 (Started in FY2019)

#	Project	Research Unit	Project Leader	Phase	Status
30	Development of human aging detection through measuring abandance of age-related metabolic biomarkers	G0 Cell Unit	Mitsuhiro Yanagida	ITR	Finished
29	Proof of concept of Inlet flap extension for tapered Duct Wave Energy Converter	Quantum Wave Microscopy Unit	Tsumoru Shintake	Phase I	Finished
28	Sulfone substituted complex cyclopropanes and linear hydrocarbons via catalysis	Science and Technology Group	Eugene Khaskin	Phase I	Finished
27	Lysosome Targeted Molecular Self-assembly for Cancer Therapeutics	Bioinspired Soft Matter Unit	Ye Zhang	ITR	Finished
26	Development of Methods for determining the structures of small compounds using mass and ion-mobility of fragment ions	Evolutionary Neurobiology Unit	Eisuke Hayakawa	Phase I	Finished
25	Laser-driven Microplasma Extreme-UV source	Femtosecond Spectroscopy Unit	Keshav Dani	ITR	Finished
24	ADHD Parenting program	Human Developmental Neurobiology Unit	Gail Tripp	ITR	Finished
23	Portable nanoplasmonics for application specific remote biosensing	Micro/Bio/Nanofluidics Unit	Amy Shen	Phase II	Finished
22	Optimisation of selective treatment of distillery and fermentation waste using Microbial Fuel Cells	Biological Systems Unit	Igor Goryanin	Phase II	Finished
21	All-solid-state Li-ion batteries with improved stability	Energy Materials and Surface Sciences	Yabing Qi	ITR	Finished
20	Methodological Innovation to Control the Outbreak of Crown-of-Thorns Starfish(COTS)in Coral Reefs	Marine Genomics Unit	Nori Satoh	ITR	Finished

Round 4 (Started in FY2018)

#	Project	Research Unit	Project Leader	Phase	Status
19	Commercialization of OIST Rice	Plant Epigenetics Unit	Hidetoshi Saze	Phase I	Finished
18	Cell-free synthesis of cellulose nanofiber	Marine Genomics Unit	Nori Satoh	Phase I	Finished
17	Development of a fast image regularization device	Structural Cellular Biology	Ulf Skoglund	Phase I	Finished
16	Development of system for determining the aging degree by blood metabolites as index	G0 Cell Unit	Mitsuhiro Yanagida	Phase I	Finished
15	Rapid, discrete, and portable device for point-of-care sexually transmitted infection (STI) diagnostics	Micro/Bio/Nanofluidics Unit	Amy Shen	Phase I	Finished
14	Anion exchange hydrogels for phosphate and nitrate removal from wastewaters	Biological Systems Unit	Igor Goryanin	Phase I	Finished
13	Scaling up of large-area solar cells	Energy Materials and Surface Sciences	Yabing Qi	Phase II	Finished

Round 3 (Started in FY2016/2017/2018)

#	Project	Research Unit	Project Leader	Phase	Status
12	New Contactless Magnetic Couplings for Applications in Microfluidics, Renewable Energy, and Nautical Propulsion	Mechanics and Materials Unit	Eliot Fried	Phase I	Finished
11	High throughput portable LSPR system for bio/chemical analysis	Micro/Bio/Nanofluidics Unit	Amy Shen	Phase I	Finished
10	Privacy preserving real-time data analysis platform	Integrated Open Systems Unit	Hiroaki Kitano	Phase I	Finished
9	Development of a facile process to deposit smooth organic– inorganic hybrid perovskite films for large area photovoltaic applications	Energy Materials and Surface Sciences	Yabing Qi	Phase I	Finished

Round 2 (Started in FY2016/2017)

#	Project	Research Unit	Project Leader	Phase	Status
8	Laser controlled liposome drug delivery system	Neurobiology Research Unit	Jeff Wickens	Phase I	Finished
7	Next generation label-free biosensors	Nanoparticles by Design	Mukhles Sowwan	Phase I	Finished
6	Developing microbial fuel cells for bioethanol process improvement through substrate-directed bacterial community enrichment	Biological Systems Unit	Igor Goryanin	Phase I	Finished

Round 1 (Started in FY2016)

#	Project	Research Unit	Project Leader	Phase	Status
5	In vitro synthesis of high molecular weight cellulose	Marine Genomics Unit	Nori Satoh	Phase I	Finished
4	Second generation tubular microbial fuel cells	Biological Systems Unit	Igor Goryanin	Phase I	Finished
3	Hydrolase-like peptide to cleave amyloid-beta protein	Cell Signal Unit	Tadashi Yamamoto	Phase I	Finished
2	Smart Gas Sensing Platform for Mobile Devices	Nanoparticles by Design	Mukhles Sowwan	Phase I	Finished
1	Large Area Perovskite Solar Cells by Chemical Vapor Deposition	Energy Materials and Surface Sciences	Yabing Qi	Phase I	Finished