Takahashi Unit's Research on Alpha-synuclein in Parkinson's in the News
Research results from the Cellular and Molecular Synaptic Function Unit unearthed new knowledge about the toxic role of the protein alpha-synuclein when overabundant in neurons: inhibiting vesicle endosytosis at the nerve terminal. The researchers believe that this inhibitory process is what occurs in the early stages of Parkinson’s disease, before morphological changes such as the loss of function and death of neurons begins.
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