Research Units

The Cell Division Dynamics Unit studies the mechanisms of chromosome segregation and cell fate determination during mitosis with a focus on mitotic spindle assembly and positioning in cultured human cells and Medaka embryos.

Every day, millions of cells divide to sustain essential tissue functions. Errors in this process can lead to developmental disorders or cancer. Our research focuses on the molecular mechanisms of cell division and quality control in both normal and cancer cells, aiming to uncover how cells maintain genomic stability and regulate proliferation. By integrating high-throughput imaging, gene editing, and genome-wide screening, we seek to expand our understanding of these fundamental processes and how their dysregulation contributes to cancer. Our lab is driven by a curiosity-based approach, grounded in the belief that fundamental research is essential for uncovering the principles that govern life. By investigating the intricate mechanisms controlling cell division, genome maintenance, and cellular quality control, we aim to reveal how these processes go awry in cancer. Through this knowledge, we strive to identify cancer-specific vulnerabilities, discover novel biomarkers, and open new avenues for targeted therapeutic strategies.

Micro/Bio/Nanofluidic Unit develops lab-on-a-chip devices to probe fluid flows and discover new flow phenomena in microscopic worlds, with applications in biotechnology.

Nucleic acids DNA and RNA are fundamental building blocks of life. These biomolecules display remarkable chemical functions such as information storage, catalysis, and molecular recognition....