30 Oct 2018
An international team of researchers at OIST and University of Otago have used the Nobel-winning cryo-electron microscopy method to reconstruct the structure of Seneca Valley virus, abbreviated...
Type: Video
30 Oct 2018
Seneca Valley Virus sounds like the last bug you’d want to catch, but it could be the next breakthrough cancer therapy. Now, scientists at the Okinawa Institute of Science and Technology (OIST) and...
Type: Press release
23 Oct 2018
Prof. Matthias Wolf co-senior authored the first study to detail how the Seneca Valley Virus interacts with its preferred receptor on tumors, ANTXR1.
Type: Photo
23 Oct 2018
A cryo-EM map of the receptor decorated capsid in which a single protomer was replaced with the atomic model. Seneca Valley Virus capsid proteins are shown in blue, green, and red, and the ANTXR1...
Type: Photo
18 Oct 2018
Filamentous Ebola viruses budding from the surface of a host cell captured by a scanning electron microscope. In common with other viruses, Ebola virus infects a host cell and utilize its machinery...
Type: Photo
18 Oct 2018
A tour of a 3D rendering and atomic model of the Ebola virus nucleocapsid core based upon the cryo-EM reconstruction created by the OIST team.      
Type: Video
18 Oct 2018
Researchers at the Okinawa Institute of Science and Technology Graduate University (OIST) have for the first time imaged the structure of a central component of...
Type: Press release
18 Oct 2018
Left: Dr. Yukihiko Sugita in front of his desk at the current affiliation, Institute for Protein Research, Osaka University. Right: Prof Matthias Wolf with a Cryo-EM microscope at OIST.  ...
Type: Photo
18 Oct 2018
Left: The Ebola virus consists of the lipid bilayer (envelope), several kinds of the viral protein, and the genomic RNA. Right: The NP-RNA complex inside the virus forms a helical structure....
Type: Photo
18 Oct 2018
Left: A 3D rendering of the cryo-EM reconstruction. The RNA and NP are colored in red and grey, respectively. A single NP molecule is highlighted in blue. Right: An atomic model of a single NP...
Type: Photo
12 Jan 2018
Made up of nucleosomes—roll-shaped bundles of DNA and protein—heterochromatin is connected by a velcro-like feature called Heterochromatin Protein 1.  
Type: Photo
12 Jan 2018
Housed in the nucleus, chromatin consists of tightly packed DNA and proteins. A form of chromatin, heterochromatin has proven difficult to image due to its flexibility and very small size.
Type: Photo
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