onu FY2013 Annual Report 8
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Figure 6: (A, B) TC neurons are stimulated by glutamate application to the distal dendrites and by activation of axons coming from retina, called optical tract. Optical tract stimulation of a slightly depolarized neuron results in unreliable action potential generation (C, left). Glutamate stimulation results in a plateau potential in the dendrite (not shown) and soma (C, middle). Stimulation of the optical tract during a plateau potential strongly increases the reliability of action potential transmission (C, right). This shows that NMDA spike/plateau potentials are needed for reliable gating of information coming from ganglion cells of the retina.
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