g0 FY2014 Annual Report Figure 4

g0 FY2014 Annual Report Figure 4

Figure 4: Schematized opening, (auto)phosphorylation and dephosphorylation of the hinge. Schematized whole condensin shown at right top. The phosphorylated hinge is presumed to be unable to bind ssDNA (red DNA rod with the crossed arrow). This hypothesis is based on two crystal structures (closed and opened) of the hinge. Hinges of Cut3/SMC4 (in yellow) and Cut14/SMC2 (in green) are illustrated, showing locations of thiophosphorylated residues.

Date:
28 February 2024
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