Seminar by Prof. Mike Fainzilber has been cancelled.
Speaker: Mike Fainzilber, Professor in Molecular Neuroscience, Head, Department of Biomolecular Sciences, Weizmann Institute of Science, Israel [website]
Title: How does a neuron grow?
Abstract: Neurons are the longest cells known, with axons that can extend to lengths 3-4 orders of magnitude greater than their cell body diameters. How can neurons sense the lengths of such long processes and control their growth? I will detail a mechanism whereby importins, molecular motors and RNA binding proteins function in a bidirectional mechanism of intracellular communication, consisting of anterograde RNA transport, local translation at axon tips, and retrograde transport of the resulting proteins, for neuron length sensing and growth control.